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1: Davinelli S, Medoro A, Intrieri M, Saso L , Scapagnini G, Kang JX. Targeting NRF2-KEAP1 axis by Omega-3 fatty acids and their derivatives: Emerging opportunities against aging and diseases. Free Radic Biol Med. 2022 Nov 20;193(Pt 2):736-750. doi: 10.1016/j.freeradbiomed.2022.11.017. Epub 2022 Nov 17. PMID: 36402440.

2: Gallorini M, Carradori S, Resende DISP, Saso L , Ricci A, Palmeira A, Cataldi A, Pinto M, Sousa E. Natural and Synthetic Xanthone Derivatives Counteract Oxidative Stress via Nrf2 Modulation in Inflamed Human Macrophages. Int J Mol Sci. 2022 Nov 1;23(21):13319. doi: 10.3390/ijms232113319. PMID: 36362104; PMCID: PMC9659273.

3: Profumo E, Maggi E, Arese M, Di Cristofano C, Salvati B, Saso L, Businaro R, Buttari B. Neuropeptide Y Promotes Human M2 Macrophage Polarization and Enhances p62/SQSTM1-Dependent Autophagy and NRF2 Activation. Int J Mol Sci. 2022 Oct 27;23(21):13009. doi: 10.3390/ijms232113009. PMID: 36361795; PMCID: PMC9653849.

4: Panieri E, Telkoparan-Akillilar P, Saso L. NRF2, a crucial modulator of skin cells protection against vitiligo, psoriasis, and cancer. Biofactors. 2022 Oct 30. doi: 10.1002/biof.1912. Epub ahead of print. PMID: 36310374.

5: Ghareghomi S, Habibi-Rezaei M, Arese M, Saso L , Moosavi-Movahedi AA. Nrf2 Modulation in Breast Cancer. Biomedicines. 2022 Oct 21;10(10):2668. doi: 10.3390/biomedicines10102668. PMID: 36289931; PMCID: PMC9599257.

6: Buttari B, Arese M, Oberley-Deegan RE, Saso L, Chatterjee A. NRF2: A crucial regulator for mitochondrial metabolic shift and prostate cancer progression. Front Physiol. 2022 Sep 23;13:989793. doi: 10.3389/fphys.2022.989793. PMID: 36213236; PMCID: PMC9540504.

7: Gray NE, Farina M, Tucci P, Saso L. The Role of the NRF2 Pathway in Maintaining and Improving Cognitive Function. Biomedicines. 2022 Aug 21;10(8):2043. doi: 10.3390/biomedicines10082043. PMID: 36009590; PMCID: PMC9405981.

8: Egbujor MC, Buttari B, Profumo E, Telkoparan-Akillilar P, Saso L. An Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their Antioxidant Effects. Int J Mol Sci. 2022 Jul 30;23(15):8466. doi: 10.3390/ijms23158466. PMID: 35955599; PMCID: PMC9369284.

9: Panieri E, Pinho SA, Afonso GJM, Oliveira PJ, Cunha-Oliveira T, Saso L. NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells. Cells. 2022 Aug 4;11(15):2401. doi: 10.3390/cells11152401. PMID: 35954245; PMCID: PMC9367715.

10: Egbujor MC, Petrosino M, Zuhra K, Saso L. The Role of Organosulfur Compounds as Nrf2 Activators and Their Antioxidant Effects. Antioxidants (Basel). 2022 Jun 26;11(7):1255. doi: 10.3390/antiox11071255. PMID: 35883746; PMCID: PMC9311638.

11: Hussain Y, Khan H, Alsharif KF, Hayat Khan A, Aschner M, Saso L. The Therapeutic Potential of Kaemferol and Other Naturally Occurring Polyphenols Might Be Modulated by Nrf2-ARE Signaling Pathway: Current Status and Future Direction. Molecules. 2022 Jun 28;27(13):4145. doi: 10.3390/molecules27134145. PMID: 35807387; PMCID: PMC9268049.

12: Suzen S, Tucci P, Profumo E, Buttari B, Saso L . A Pivotal Role of Nrf2 in Neurodegenerative Disorders: A New Way for Therapeutic Strategies. Pharmaceuticals (Basel). 2022 May 31;15(6):692. doi: 10.3390/ph15060692. PMID: 35745610; PMCID: PMC9227112.

13: Yaylim İ, Farooqi AA, Telkoparan-Akillilar P, Saso L. Interplay between Non-coding RNAs and NRF2 in Different Cancers: Spotlight on miRNAs and Long non-coding RNAs. J Pharmacol Exp Ther. 2022 Jun 6:JPET-MR-2021-000921. doi: 10.1124/jpet.121.000921. Epub ahead of print. PMID: 35667688.

14: Shahcheraghi SH, Salemi F, Alam W, Ashworth H, Saso L, Khan H, Lotfi M. The Role of NRF2/KEAP1 Pathway in Glioblastoma: Pharmacological Implications. Med Oncol. 2022 May 15;39(5):91. doi: 10.1007/s12032-022-01693-0. PMID: 35568790.

15: Hussain Y, Abdullah, Alsharif KF, Aschner M, Theyab A, Khan F, Saso L, Khan H. Therapeutic Role of Carotenoids in Blood Cancer: Mechanistic Insights and Therapeutic Potential. Nutrients. 2022 May 6;14(9):1949. doi: 10.3390/nu14091949. PMID: 35565917; PMCID: PMC9104383.

16: Gall Trošelj K, Tomljanović M, Jaganjac M, Matijević Glavan T, Čipak Gašparović A, Milković L, Borović Šunjić S, Buttari B, Profumo E, Saha S, Saso L, Žarković N. Oxidative Stress and Cancer  Heterogeneity Orchestrate NRF2 Roles Relevant for Therapy Response. Molecules. 2022 Feb 22;27(5):1468. doi: 10.3390/molecules27051468. PMID: 35268568; PMCID: PMC8912061.

17: Saha S, Buttari B, Profumo E, Tucci P, Saso L . A Perspective on Nrf2 Signaling Pathway for Neuroinflammation: A Potential Therapeutic Target in Alzheimer’s and Parkinson’s Diseases. Front Cell Neurosci. 2022 Jan 21;15:787258. doi: 10.3389/fncel.2021.787258. PMID: 35126058; PMCID: PMC8813964.

18: Davinelli S, Saso L, D’Angeli F, Calabrese V, Intrieri M, Scapagnini G. Astaxanthin as a Modulator of Nrf2, NF-κB, and Their Crosstalk: Molecular Mechanisms and Possible Clinical Applications. Molecules. 2022 Jan 14;27(2):502. doi: 10.3390/molecules27020502. PMID: 35056816; PMCID: PMC8779084.

19: Shahcheraghi SH, Salemi F, Peirovi N, Ayatollahi J, Alam W, Khan H, Saso L. Nrf2 Regulation by Curcumin: Molecular Aspects for Therapeutic Prospects. Molecules. 2021 Dec 28;27(1):167. doi: 10.3390/molecules27010167. PMID: 35011412; PMCID: PMC8746993.

20: Seminotti B, Grings M, Tucci P, Leipnitz G, Saso L. Nuclear Factor Erythroid-2-Related Factor 2 Signaling in the Neuropathophysiology of Inherited Metabolic Disorders. Front Cell Neurosci. 2021 Nov 26;15:785057. doi: 10.3389/fncel.2021.785057. PMID: 34955754; PMCID: PMC8693715.

21: Ghareghomi S, Rahban M, Moosavi-Movahedi Z, Habibi-Rezaei M, Saso L, Moosavi-Movahedi AA. The Potential Role of Curcumin in Modulating the Master Antioxidant Pathway in Diabetic Hypoxia-Induced Complications. Molecules. 2021 Dec 17;26(24):7658. doi: 10.3390/molecules26247658. PMID: 34946740; PMCID: PMC8706440.

22: Farina M, Vieira LE, Buttari B, Profumo E, Saso L . The Nrf2 Pathway in Ischemic Stroke: A Review. Molecules. 2021 Aug 18;26(16):5001. doi: 10.3390/molecules26165001. PMID: 34443584; PMCID: PMC8399750.

23: Ucar BI, Ucar G, Saha S, Buttari B, Profumo E, Saso L. Pharmacological Protection against Ischemia-Reperfusion Injury by Regulating the Nrf2-Keap1-ARE Signaling Pathway. Antioxidants (Basel). 2021 May 21;10(6):823. doi: 10.3390/antiox10060823. PMID: 34063933; PMCID: PMC8224095.

24: Sezgin-Bayindir Z, Losada-Barreiro S, Bravo-Díaz C, Sova M, Kristl J, Saso L. Nanotechnology-Based Drug Delivery to Improve the Therapeutic Benefits of NRF2 Modulators in Cancer Therapy. Antioxidants (Basel). 2021 Apr 27;10(5):685. doi: 10.3390/antiox10050685. PMID: 33925605; PMCID: PMC8145905. 

25: Aleksic M, Kalezic A, Saso L, Jankovic A, Korac B, Korac A. The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism. Antioxidants (Basel). 2021 Apr 12;10(4):591. doi: 10.3390/antiox10040591. PMID: 33921249; PMCID: PMC8068806.

26: Süntar I, Çetinkaya S, Panieri E, Saha S, Buttari B, Profumo E, Saso L. Regulatory Role of Nrf2 Signaling Pathway in Wound Healing Process. Molecules. 2021 Apr 21;26(9):2424. doi: 10.3390/molecules26092424. PMID: 33919399; PMCID: PMC8122529.

27: Buha A, Baralić K, Djukic-Cosic D, Bulat Z, Tinkov A, Panieri E, Saso L. The Role of Toxic Metals and Metalloids in Nrf2 Signaling. Antioxidants (Basel). 2021 Apr  1;10(5):630. doi: 10.3390/antiox10050630. PMID: 33918986; PMCID: PMC8142989.

28: Telkoparan-Akillilar P, Panieri E, Cevik D, Suzen S, Saso L. Therapeutic Targeting of the NRF2 Signaling Pathway in Cancer. Molecules. 2021 Mar 5;26(5):1417. doi: 10.3390/molecules26051417. PMID: 33808001; PMCID: PMC7961421.

29: Tascioglu Aliyev A, Panieri E, Stepanić V, Gurer-Orhan H, Saso L. Involvement of NRF2 in Breast Cancer and Possible Therapeutical Role of Polyphenols and Melatonin. Molecules. 2021 Mar 25;26(7):1853. doi: 10.3390/molecules26071853. PMID: 33805996; PMCID: PMC8038098.

30: Egbujor MC, Saha S, Buttari B, Profumo E, Saso L. Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress. Expert Rev Clin Pharmacol. 2021 Apr;14(4):465-480. doi: 10.1080/17512433.2021.1901578. Epub 2021 Mar 30. PMID: 33691555.

31: Panieri E, Saso L. Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells. Antioxid Redox Signal. 2021 Jun 20;34(18):1428-1483. doi: 10.1089/ars.2020.8146. Epub 2021 Feb 19. PMID: 33403898.

32: Rahban M, Habibi-Rezaei M, Mazaheri M, Saso L, Moosavi-Movahedi AA. Anti-Viral Potential and Modulation of Nrf2 by Curcumin: Pharmacological Implications. Antioxidants (Basel). 2020 Dec 4;9(12):1228. doi: 10.3390/antiox9121228. PMID: 33291560; PMCID: PMC7761780.

33: Saha S, Buttari B, Panieri E, Profumo E, Saso L. An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation. Molecules. 2020 Nov 23;25(22):5474. doi: 10.3390/molecules25225474. PMID: 33238435; PMCID: PMC7700122.

34: Panieri E, Telkoparan-Akillilar P, Suzen S, Saso L. The NRF2/KEAP1 Axis in the Regulation of Tumor Metabolism: Mechanisms and Therapeutic Perspectives. Biomolecules. 2020 May 20;10(5):791. doi: 10.3390/biom10050791. PMID: 32443774; PMCID: PMC7277620.

35: Panieri E, Buha A, Telkoparan-Akillilar P, Cevik D, Kouretas D, Veskoukis A, Skaperda Z, Tsatsakis A, Wallace D, Suzen S, Saso L. Potential Applications of NRF2 Modulators in Cancer Therapy. Antioxidants (Basel). 2020 Feb 25;9(3):193. doi: 10.3390/antiox9030193. PMID: 32106613; PMCID: PMC7139512.

36: Panieri E, Saso L. Potential Applications of NRF2 Inhibitors in Cancer Therapy. Oxid Med Cell Longev. 2019 Apr 11;2019:8592348. doi: 10.1155/2019/8592348. PMID: 31097977; PMCID: PMC6487091.

37: Telkoparan-Akillilar P, Suzen S, Saso L. Pharmacological Applications of Nrf2 Inhibitors as Potential Antineoplastic Drugs. Int J Mol Sci. 2019 Apr 24;20(8):2025. doi: 10.3390/ijms20082025. PMID: 31022969; PMCID: PMC6514836.

38: Armagan G, Sevgili E, Gürkan FT, Köse FA, Bilgiç T, Dagcı T, Saso L. Regulation of the Nrf2 Pathway by Glycogen Synthase Kinase-3 β in MPP⁺-Induced Cell Damage. Molecules. 2019 Apr 8;24(7):1377. doi: 10.3390/molecules24071377. PMID: 30965670; PMCID: PMC6480928.

39: Macáková K, Afonso R, Saso L, Mladěnka P. The influence of alkaloids on oxidative stress and related signaling pathways. Free Radic Biol Med. 2019 Apr;134:429-444. doi: 10.1016/j.freeradbiomed.2019.01.026. Epub 2019 Jan 29. PMID: 30703480.

40: Sova M, Saso L. Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review. Drug Des Devel Ther. 2018 Sep 25;12:3181-3197. doi: 10.2147/DDDT.S172612. PMID: 30288023; PMCID: PMC6161735.

41: Milkovic L, Zarkovic N, Saso L. Controversy about pharmacological modulation of Nrf2 for cancer therapy. Redox Biol. 2017 Aug;12:727-732. doi: 10.1016/j.redox.2017.04.013. Epub 2017 Apr 8. PMID: 28411557; PMCID: PMC5393166.

42: Carvalho AN, Firuzi O, Gama MJ, Horssen JV, Saso L. Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope? Curr Drug Targets. 2017 Mar 30;18(6):705-718. doi: 10.2174/1389450117666160401120514. PMID: 27033198.

43: Cort A, Ozben T, Saso L, De Luca C, Korkina L. Redox Control of Multidrug Resistance and Its Possible Modulation by Antioxidants. Oxid Med Cell Longev. 2016;2016:4251912. doi: 10.1155/2016/4251912. Epub 2016 Jan 5. PMID: 26881027; PMCID: PMC4736404.

44: Moosavi F, Hosseini R, Saso L, Firuzi O. Modulation of neurotrophic signaling pathways by polyphenols. Drug Des Devel Ther. 2015 Dec 21;10:23-42. doi: 10.2147/DDDT.S96936. PMID: 26730179; PMCID: PMC4694682.

45: Ramprasath T, Vasudevan V, Sasikumar S, Puhari SS, Saso L, Selvam GS. Regression of oxidative stress by targeting eNOS and Nrf2/ARE signaling: a guided drug target for cardiovascular diseases. Curr Top Med Chem. 2015;15(9):857-71. doi: 10.2174/1568026615666150220114417. PMID: 25697563.

46: Venkateswaran K, Verma A, Bhatt AN, Agrawala PK, Raj HG, Malhotra S, Prasad AK, Wever OD, Bracke ME, Saso L, Parmar VS, Shrivastava A, Dwarakanath BS. Modifications of cell signalling and redox balance by targeting protein acetylation using natural and engineered molecules: implications in cancer therapy. Curr Top Med Chem. 2014;14(22):2495-507. doi: 10.2174/1568026614666141203122005. PMID: 25478886.

47: Saso L , Firuzi O. Pharmacological applications of antioxidants: lights and shadows. Curr Drug Targets. 2014;15(13):1177-99. doi: 10.2174/1389450115666141024113925. PMID: 25341421.